Inclusion Criteria:

- Invasive non-lobular breast cancer, histologically proven by biopsy

- Tumour T2 - T3 regardless of nodal status, stemming from a primary surgery, in whom
FDG-PET is performed for staging

- Age greater than or equal to 18 years

- Good condition: WHO lower 2.

- Women receiving effective contraception throughout the duration of treatment and 3
months after cessation of treatment,

- Patient has signed informed consent

Exclusion Criteria:

- Carcinoma other than breast ductal carcinoma.

- Patients for whom no target tumor is assessable.

- Patients for whom surgery first of their breast cancer is not indicated (tumor
spread, metastasis, general health, co-morbidities).

- Pregnant women, or likely to be during breastfeeding.

- Major protected (under supervision and under guardianship)

- Failure to submit to medical supervision of the study for reasons of geography,
social or psychological

- Incomplete tumor resection