Prospective Pilot Study of Multimodal Radiological Evaluation Feasibility During Chemoradiotherapy of Rectal Adenocarcinomas.
The objective of the present project is to validate the feasibility of a multimodal
radiological pathway while on chemoradiotherapy, in order to validate potentially predictive
factors for chemoradiotherapy sensitivity of rectal adenocarcinomas.
It is based on a structured clinical and radiological pathway for patients, using diffusion
MRI and F misonidazole PET.
Validation of these new tools is already needed in clinical practice since future
institutional trials will be based on treatment individualisation, using preoperative
predicting factors.
Interventional
Endpoint Classification: Safety Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic
acceptation rate of the entire sequence by eligible patients
acceptation rate of the entire sequence by eligible patients
13 weeks
Yes
Guillaume Portier, PhD
Principal Investigator
CHU Toulouse
France: Afssaps - Agence française de sécurité sanitaire des produits de santé (Saint-Denis)
0932103
NCT01619696
March 2011
December 2012
Name | Location |
---|