A Phase II Study of Bandage Lenses for Ocular Graft-versus-Host Disease After Allogeneic Hematopoietic Cell Transplantation
I. To determine the symptom improvement after 2 weeks of therapy with bandage lenses.
I. To confirm short-term safety within 1 month after bandage lenses. II. To determine
improvement in ophthalmologic examinations after bandage lenses.
III. To test optical coherence tomography as an objective measure of corneal inflammation.
Patients wear bandage lenses continuously for at least 3 months in the absence of disease
progression or unacceptable toxicity.
Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Supportive Care
Eye subscale of the Lee symptom scale
After 2 weeks of bandage lenses use
Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium
United States: Federal Government
|Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium||Seattle, Washington 98109|