Inclusion Criteria:

- Patients had sufficient medical records (anthropometric, endocrine, metabolic, lipid
parameters) and age less than 45.

Exclusion Criteria:

1. Women who experienced menarche <3 years before the beginning of the study;

2. Women who received hormones or drugs for major medical diseases;

3. Women who presented ovarian cysts or ovarian tumors, uterine abnormality;

4. Women who were >45 years old.