Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
change in 28-joint disease activity index( DAS28)
disease activity score 28 formula which caculates based the number of tenderness and swelling of 28 joints and also ESR)
Study duration was 6 months and the subjects were assessed for DAS 28 change at baseline, after 2 , 16 and 24 weeks.
Islamic Repablic of Iran:National ethics committee