Inclusion Criteria:

- Patients who have signed this Written Informed Consent Form after a full explanation
about the participation in this study

- Patients aged 18 years or older Patients diagnosed with a solid malignant tumour or
malignant lymphoma that is refractory to standard therapies or for which no standard
therapies exist

- Patients with good physical conditions (you can walk and can look after yourself)
within the last 2 weeks.

- Patients who have at least one lesion that can be accurately assessed

Exclusion Criteria:

- Patients who have recently received or are receiving prohibited medications or
treatments

- Patients who have any unresolved side effects of previous treatments

- Patients who have spinal cord compression or brain metastases

- Patients who have severe systemic diseases (e.g., uncontrolled hypertension,
hepatitis B, hepatitis C and human immunodeficiency virus [HIV] infection)

- Patients with significant abnormal ECG findings