Inclusion Criteria:

- more than 18 years old

- patient with diagnosis of liver cirrhosis Child Pugh A-B

- Patients without previous hepatocellular carcinoma in whom ultrasound detects a
suspicious hepatic lesion; solitary solid and well-defined nodule between 10 and 20mm

- patients in whom diagnosis of hepatocellular carcinoma is a clinical need prior to
treatment indication

- patient that agree to participate signing informed consent form

Exclusion Criteria:

- Patients with poor liver function who would have undergone transplantation even
without hepatocellular carcinoma diagnosis (Child-Pugh C)

- patients with previous diagnosis of hepatocellular carcinoma

- patients with significant comorbidities that could prevent the optimum therapeutic
decision in case of positive diagnosis of hepatocellular carcinoma

- patients with severe clotting alterations that contraindicate the fine-needle biopsy
-Patients with chronic kidney disease or glomerular filtration rate < 30 ml/min

- patients with contraindications to perform magnetic resonance imaging (pacemaker,
claustrophobia...)

- Known hypersensitivity to study drugs or excipients

- pregnancy or breastfeeding