Assessment of Septin9 Biomarker for Detection of Colorectal Cancer in Patients With Positive Fecal Immunochemical Test
Observational Model: Case-Only, Time Perspective: Prospective
Performance characteristics of the Septin 9 biomarker among patients who have a positive FIT result
Sensitivity, specificity, positive predictive value, and negative predictive value of Septin 9 (relative to colonoscopy) for detecting CRC in a sample of individuals with a positive test result for single-sample OC-Micro FIT using various thresholds for Septin 9 positivity.
Participants are prospectively enrolled. Eligible participants will be asked to provide a blood sample at least 2 days prior to receiving a colonoscopy. The timeframe for participation will generally be within 3 months of receiving a positive FIT result.
Gloria Coronado, PhD
Kaiser Permanente, Center for Health Research NW
United States: Institutional Review Board
Septin 9 Colorectal Biomarker
|Kaiser Permanente Northwest||Portland, Oregon 97227|
|Kaiser Permanente Georgia||Atlanta, Georgia 30300|