Trial Information

Music Video for AYA-Parent Communication and Resilience

OBJECTIVES:

- Compare the efficacy of a Therapeutic Music Video (TMV) intervention with a Therapeutic
Music Video plus Parent (TMV+P) intervention on outcomes for adolescents/young adults
(AYA) undergoing treatment for high-risk cancer.

- Compare the efficacy of a TMV intervention with a TMV+P intervention on outcomes for
parents of AYA with high-risk cancer.

- Determine relationships of parent distress and parent perceived family environment with
AYA outcomes using a mixed methods approach. (exploratory)

OUTLINE: This is a multicenter study. Patients are stratified according to age in years
(11-13 vs 14-17 vs 18-24). Parents are randomized to 1 of 2 intervention arms.

- Arm I (TMV, low-dose parent): AYA patients undergo 60-minute sessions, delivered in a
private setting during outpatient clinic visits or hospitalizations, within a 6-8 weeks
period with board-certified music therapists. The music therapists help patients in
brainstorming and lyric writing, singing and creatively exploring how AYA lyrics and
structure of the selected music fit together, recording their song with a digital
accompaniment track, completing video layout worksheets (determining the contents of
the video), taking and gathering photos or making drawings for the video, and viewing
clip art and pictures on a computer. The music therapist then digitally formats,
compiles, and transfers the AYA-developed music video to a DVD. When completed, the
therapist shares the video with the AYA and offers the option of having a video
"premiere." AYAs who choose a premiere select a date and time for the viewing and
identify individuals they wish to attend (family, friends, healthcare professionals).
After the viewing, AYAs receive a copy of their DVD to keep. Parents' presence and
involvement during all sessions are directed by the AYAs. Parents receive 2 sessions
over 15-60 minutes with a trained study team. During the first session, parents receive
handouts of helpful website resources that have specific information to help parents
support their AYAs. Team members also assure that parents know how to assess the sites.
During the second session, parents receive audio-recorded, telephone-based contact by a
trained nurse who asks them questions focusing on the content available on the provided
website. The trained nurse also answers any questions parents may have.

- Arm II (AYA TMV +P): AYA patients receive intervention as patients in arm I. Parents
receive 3 tailored 60-minute sessions with a trained nurse intervener. Sessions are
recorded to make sure study nurse delivers the sessions according to the study
protocol. Study nurse provides support information to parents using the Robb's
Contextual Support Model, including Managing the Chaos: Self Care as the First Step to
Caring for Your AYA, Relationship Support: How to Listen to and Encourage Your AYA to
Talk; and Strategies for AYA Autonomy Support: Understanding AYA's Ways of Coping.
Session 3 content is also based on the Resilience in Illness model. Sessions are also
tailored to parents' needs, skills practice and/or role playing, and reflection on and
reinforcement of learning. Parents receive written materials on tips and prescribed
skills practice plans.

AYA and parents complete questionnaires including Illness-Related Distress, Defensive
Coping, Spiritual Perspective, Social Integration, Family Environment questionnaires,
Hope-Derived Meaning, Self-Transcendence, Positive Coping, Resilience, Parent Distress, and
Quality of Life at baseline, at 2 weeks after final session, and then at 90 days after final
intervention session. Medical background, intensity of treatment rating scale, and family
demographics are also collected.