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Tumor-Associated Macrophages Correlate With Response and Outcomes in Advanced Non-Small Cell Lung Cancer After First Line Treatment.


N/A
20 Years
N/A
Not Enrolling
Both
Advanced Nonsmall Cell Lung Cancer

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Trial Information

Tumor-Associated Macrophages Correlate With Response and Outcomes in Advanced Non-Small Cell Lung Cancer After First Line Treatment.


Inclusion Criteria:



- advanced NSCLC,

- more than 20 years old,

- measurable tumor,

- response and outcome recorded after the first line treatment.

Exclusion Criteria:

- Early stage NSCLC,

- less than 20 years,

- pregnancy,

- unmeasurable NSCLC.

Type of Study:

Observational

Study Design:

Observational Model: Cohort, Time Perspective: Retrospective

Outcome Measure:

Response to treatment of advanced NSCLC with high or low TAM.

Outcome Description:

All patients with advanced non-small cell lung cancer (NSCLC) who had been treated were included. The decision of advanced NSCLC treatment was a consensus by the patient and clinician, and approved by team conference (including the oncologists, pulmonologists, pathologists, radiologists, surgeons, radiation oncologists, and nuclear medicine specialists). The tumor response was evaluated using computerized tomography according to the Response Evaluation Criteria in Solid Tumors (RECIST). The treatment response of advanced between high and low TAM patients were compared.

Outcome Time Frame:

2-3 months

Safety Issue:

No

Principal Investigator

Fu-Tsai Chung, M.D.

Investigator Role:

Principal Investigator

Investigator Affiliation:

Chang Gung Memorial Hospital

Authority:

Taiwan : Food and Drug Administration

Study ID:

100-0522B

NCT ID:

NCT01551251

Start Date:

January 2006

Completion Date:

December 2010

Related Keywords:

  • Advanced Nonsmall Cell Lung Cancer
  • Carcinoma, Non-Small-Cell Lung
  • Lung Neoplasms

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