Inclusion Criteria:

- Patient (e) old (e) over 18 years

- Patients with squamous cell carcinoma of head and neck (oral cavity, oropharynx,
lymphadenopathy without gateway) histologically proven.

- Patient targeted for head and neck radiotherapy by Tomotherapy exclusive with or
without concurrent chemotherapy (containing platinum)

- Indication of head and neck radiotherapy bilateral

- All of the TNM stage except metastatic

- Patient has signed informed consent for participation in the study

- Mastery of the French language

Exclusion Criteria:

- History of head and neck radiotherapy

- Indication of head and neck radiotherapy unilateral

- Personal history of malignant tumors uncontrolled over the past 5 years

- History of oral sicca syndrome

- Surgical removal of one or more salivary glands (parotid, submandibular gland,
sublingual gland)

- Concomitant treatment with amifostine

- Concomitant treatment with cetuximab

- Primary tumor of the salivary glands

- Neoadjuvant Chemotherapy

- Head and neck hyperfractionated radiotherapy and / or accelerated

- Head and neck radiotherapy hypofractionated

- Metastatic disease

- Patient deprived of liberty, under guardianship

- Any medical condition or psychological associate that could compromise the patient's
ability to participate in the study

- Refusal of the patient.