Study of TPF (Docetaxel, Cisplatin, 5-fluorouracil) Induction Chemotherapy Followed by Surgery and Radiotherapy in Patients With Locally Advanced and Resectable Oral Squamous Cell Carcinoma
The primary endpoint of this study is the survival rate (2, 3, 5 years) after induction
chemotherapy followed by surgery and radiotherapy. The second endpoint of this study is
locoregional control rates (1, 2 years), and the safety.
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
To evaluate the survival rate after TPF induction chemotherapy followed by surgery and radiotherapy.
Up to 5 years
Zhi-yuan Zhang, MD, PhD
Department of Oral and Maxillofacial Surger, Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University
China: Ethics Committee
TPF for resectable OSCC