Inclusion Criteria:

1. Proved diagnosis of HCC according to AASLD practice guidelines (Bruix and Sherman,
2005).

2. Patients underwent RFA for HCC with BCLC (The Barcelona-Clinic- Liver-Cancer staging
system) stage A (Bruix and Sherman, 2005) with no eligibility or ability to do
transplantation or resection.

3. Patients should be followed-up for more than 12 months to exclude early recurrence
i.e. recurrence within 1 year.

4. Patients with INR < 1.5 or prothrombin concentration > 50%.

5. Platelet count > 50000 cell/mm3.

Exclusion Criteria:

1. Presence of extra-hepatic metastasis or gross vascular invasion.

2. Child class C patients.

3. Follow up period of less than 12 months.