Inclusion Criteria:

- Women ≥ 18 years of age, with breast cancer, treated by breast conserving surgery and
scheduled to receive adjuvant radiotherapy to the breast alone

- Bra cup size ≤D

- Karnofsky performance status of ≥ 80%

- Women of childbearing potential must have a negative pregnancy test before study
entry and must agree to use a medically acceptable method of birth control throughout
the study period

- Ability to understand and willingness to sign a written informed consent document

Exclusion Criteria:

- Bilateral breast cancer

- Inflammatory breast cancer

- Lymphangiosis carcinomatosa

- Medically significant dermatologic conditions affecting the irradiated area

- Planned use of other agents with the aim of preventing and/or treating radiation
dermatitis

- Concomitant medications which might exacerbate radiation dermatitis

- History of previous radiation therapy of the breast

- Pregnancy or breastfeeding

- Having received any other investigational agent within 4 weeks before enrolment

- Uncontrolled intercurrent illness including, but not limited to psychiatric
illness/social situations that would limit compliance with study requirements