Inclusion Criteria:

- Females 50 or younger

- Histological or cytological confirmation of breast cancer

- Any clinical stage is allowed

Exclusion Criteria:

- Any known autoimmune condition, chronic steroid use, underlying immune disease (other
than breast cancer), use of immunomodulatory prescription drugs for any medical
condition.

- The presence of other comorbid conditions known to impact immune function, (such as:
type I diabetes, uncontrolled adult onset diabetes, severe chronic obstructive
pulmonary disease (COPD), uncontrolled infection or known HIV infection.)

- Underlying psychiatric condition which would, in the opinion of the investigator,
preclude compliance with study requirements

- Diagnosed with another type of cancer within 5 years except for breast cancer,
cervical or non-melanomatous skin cancer.