The Role of AF1q in Progression of Leukemia
OBJECTIVES:
- To determine the subcellular localization of the MLL-AF1q fusion protein in leukemia
cells.
OUTLINE: Cryopreserved specimens are analyzed for MLL-AF1q fusion protein and AF1 gene
expression by mass spectrometry, western blot analysis, semi-quantitative PCR, and qPCR.
Observational
N/A
Subcellular localization of the MLL-AF1q fusion protein in leukemia cells
No
Julie D. Saba, MD, PhD
Principal Investigator
Children's Hospital & Research Center Oakland
United States: Federal Government
CDR0000721339
NCT01500499
December 2011
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