Effects of Different Inspiratory to Expiratory Ratios on Intrapulmonary Shunt Fraction and Oxygenation During One Lung Ventilation in the Lateral Decubitus Position
Increasing inspiratory time(e.g. Inverse ratio ventilation) has been known that had
advantage of alveolar recruitment, preventing of ateletasis. On the contrary, it has
disadvantange of intrinsic PEEP, air trapping. There is few study on one lung ventilation in
lateral decubitus position about this ventilation method. We were going to investigate
effecf of this ventilation method.
Interventional
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
intrapulmonary shunt fraction
T1,T2,T3,T4 : ALL mesurement in lateral decubitus position T1-intrapulmonary shunt T2-intrapulmonary shunt T3-intrapulmonary shunt T4-intrapulmonary shunt
T1 (10min before one lung ventibation)T2 (30min after one lung ventilation started)T3 (60min after one lung ventilation started)T4 (10min after two lung ventilation)
Yes
Young Jun Oh, MD,PhD
Study Chair
Department of Anaesthesiology and Pain Medicine, Anaesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Korea
South Korea:Korea food and Drug Administration
1-2011-0058
NCT01499212
July 2011
December 2011
Name | Location |
---|