Inclusion Criteria:

- 18~70 year old, KPS score >50 points, estimate survival > 3 months;

- Primary lung cancer patients after chemotherapy or radiation therapy;

- Primary lung cancer patients after targeted therapy;

- Primary lung cancer patients with lung function can not accept operation or unwilling
to operation;

- Primary lung cancer recurrence or surgery can't complete resection;

- Primary lung cancer patients after intervention therapy(I125 implanted, freezing, rf,
etc.);

- No serious mental illness and no serious heart, liver, kidney diseases,
unincorporated other potentially lethal diseases;

- Patients Voluntary attempt, and informed consent.

Exclusion Criteria:

- History of cardiovascular disease: congestive heart failure > New York heart
association (NYHA) level II, unstable angina patients (resting when the angina
symptoms) or new happen angina pectoris (recent 3 months) or recent 6 months of
myocardial infarction;

- Cachexia; or other deadly diseases;

- Liver function laboratory ALT, AST more than normal limits on 2.0 times ; Or kidney
TBIL, BUN more than normal limits on 1.0 times , or Cr more than normal upper limit;

- Active infection;

- Pregnant or lactating women

- At present Is receiving other cancer treatment (such as chemotherapy, radiation
therapy, chemotherapy, immunosuppressants and thrombosis, targeted agents);

- Now or recently will join another experimental clinical study ;

- Other situations that the researchers considered unsuitable for this study (such as
mental illness, drug abuse, HIV infections, etc.), or influence on the results of
clinical trials for analysis.