Trial Information
Lacrimal Drainage Obstruction in Gastric Cancer Patients Receiving Adjuvant S-1 Chemotherapy: A Prospective Study
Inclusion Criteria:
- Patients who received curative (R0) surgery for GC
- Patients receiving adjuvant S-1 chemotherapy
- Patients with adequate major organ functions for chemotherapy
- Patient who have taken S-1 at least 7 days (for blood and tear sampling)
Exclusion Criteria:
- Patients who are not candidate for adjuvant S-1 chemotherapy
- Patients with previous history of LDO
- Patients with other opthalmologic disease who are not appropriate to be included in
this study (i.e., patients using eyedrop medication; patients with dry eye whose
tears cannot be sampled)
Type of Study:
Observational
Study Design:
Observational Model: Cohort, Time Perspective: Prospective
Outcome Measure:
The incidence of LDO
Outcome Description:
The cumulative incidence of LDO during the 1 year after adjuvant S1 chemotherapy will be analyzed
Outcome Time Frame:
The incidence of LDO (1 year)
Safety Issue:
No
Principal Investigator
Keun-Wook Lee, M.D. & Ph.D.
Investigator Role:
Principal Investigator
Investigator Affiliation:
Department of Internal Medicine, Seoul National University Bundang Hospital
Authority:
South Korea: Institutional Review Board
Study ID:
GC-SNUBH-2010-01
NCT ID:
NCT01486472
Start Date:
November 2010
Completion Date:
December 2013
Related Keywords:
- Gastric Cancer
- Adjuvant chemotherapy
- Stomach Neoplasms