Trial Information

Notch Signaling and Novel Biomarkers for Barretts Esophagus

This research study hopes to identify new molecular markers in the tissue of Barrett's
esophagus that will help physicians better understand and manage this condition. Currently
there is very little understanding as to how Barrett's esophagus develops and why some
people with Barrett's esophagus go on to develop esophageal cancer. The purpose of this
study is to develop a better understanding of how these processes occur. The investigators
also hope to use the information from this study to identify new molecular markers that the
investigators can use to better determine who will or will not go on to develop esophageal
cancer. Patients who have been diagnosed in the past with Barrett's esophagus will be asked
to participate. Patients without Barrett's esophagus will be asked to take part so that the
investigators can compare tissue from patients without the conditions to those with the
conditions.