Type of Study:

Interventional

Study Design:

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Outcome Measure:

Change from baseline in IFN-gamma plasma levels following serial QFT-GIT testing during the treatment with anti-TNF agents

Outcome Description:

QFT-GIT was performed at randomization (before commencement of anti-TNF treatment) and after 3 and 6 months since the beginning of biologicals.

Outcome Time Frame:

From date of randomization (before anti-TNF treatment) until the date of repeated QFT-GIT testing (after 12 weeks and again after 24 weeks) for a total assessment of 7 months.

Safety Issue:

Yes

Authority:

Italy: Ethics Committee

Study ID:

URomLS01

NCT ID:

NCT01475409

Start Date:

July 2008

Completion Date:

February 2011

Related Keywords:

• Inflammatory Rheumatic Diseases
• anti-TNF
• tuberculosis
• QuantiFERON-TB Gold In-Tube
• tuberculin skin test
• rheumatoid arthritis
• spondyloarthritis
• Rheumatic Diseases
• Tuberculosis