Improving Complete Endoscopic Mucosal Resection (EMR) of Colorectal Neoplasia: A Randomized Prospective Comparison of Snares and Injectate in the Resection of Large Sessile Colonic Polyps
The primary aim of the study is to compare the efficacy, efficiency and safety of two types
of snares used in Endoscopic Mucosal Resection (EMR), a combined needle and snare unit
(ISnare, US Endoscopy) versus an oval braided snare with spiral wire (Snaremaster, Olympus).
The secondary aim is to explore whether EMR efficacy and efficiency is depended upon the
injection solution used, saline versus Gonak (a solution containing HPMC, saline, and
epinephrine) for EMR.
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Factorial Assignment, Masking: Open Label, Primary Purpose: Treatment
Efficacy of Two Devices used in EMR
To explore the efficacy of two devices used in EMR (iSnare® system versus Snaremaster) as measured by the "Sydney Resection Quotient" (SRQ). SRQ is defined as "lesion size in mm divided by the number of pieces to resect" .
Timothy A Woodward, M.D.
Mayo Clinic in Florida
United States: Institutional Review Board
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