Inclusion Criteria:

Cisplatin-Based Chemotherapy Group

- Histologically-proven diagnosis of GCT

- Male

- Age ≥18

- No prior exposure to chemotherapy or radiation

- Planned to receive 3-4 cycles of cisplatin-based chemotherapy

Surgery-Only Group

- Histologically-proven diagnosis of GCT Male

- Age ≥18

- Surgical management of GCT performed less than 90 days before start of study
(includes orchiectomy and primary retroperitoneal lymph node dissection (RPLND))

- No prior exposure to chemotherapy or radiation

Exclusion Criteria:

Cisplatin-Based Chemotherapy Group

- Prior exposure to chemotherapy or radiation

- Known diagnosis or history of being diagnosed with vasculitis, autonomic dysfunction,
coronary artery disease, or collagen-vascular disease

Surgery-Only Group

- Prior exposure to chemotherapy or radiation

- Planned for non-surgical management with chemotherapy or radiation.

- Known diagnosis or history of being diagnosed with vasculitis, autonomic dysfunction,
coronary artery disease, or collagen-vascular disease.