Inclusion Criteria:

- New diagnosis of stage I or II Non-Small Cell Lung Cancer (NSCLC)

- Must have resectable disease and complete surgical resection planned

- Histologically or cytologically confirmed adenocarcinoma, squamous or large cell
carcinoma NSCLC

- No prior chemotherapy, biologic/molecular targeted therapy or radiation therapy for
this cancer

- Tumor specimen samples must be collected within 1 hour of surgery

- Patient must be at least 18 years of age

- Patient must sign and date an approved study consent form

Exclusion Criteria:

- Patients with psychiatric or addictive disorders that would preclude obtaining study
consent

- Informed consent obtained the same day as surgery

- Absence of histological diagnosis of lung cancer

- Known infectious disease

- History of chemotherapy, biologic/molecular targeted therapy or radiation therapy for
this cancer or any prior cancer or any other non-cancer diseases or illnesses, i.e.
rheumatoid arthritis