To Compare Safety and the General Imaging Pattern of Cyclotron Produced Technetium vs. Generator Produced Technetium in Patients With Thyroid Cancer
The Canadian Government supports R&D into alternative methods of medical isotope production
that  do not require the construction of new nuclear reactors,  are not dependent on
government subsidies and  will lead to a RP market. The cyclotron production model of
pertechnetate (CPERT) has received significant validation. The University of Alberta's
Edmonton PET Center and the ERC is a cyclotron/radiopharmacy unit, providing a safe, cost
effective, unsubsidized and reliable supply of RPs.
Allocation: Non-Randomized, Endpoint Classification: Safety Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Diagnostic
Safety of CPERT
CPERT safety will be assessed by evaluation of vital signs (pre-injection and post-imaging), blood haematology (pre-injection and post-imaging), SMA-12 clinical biochemistry profile (pre-injection and post-imaging) and collection of adverse events.
AJB McEwan, Msc, MB, BS
Canada: Health Canada