Trial Information

Association Of Prognosis And BRAF V600E Mutations In Papillary Thyroid Carcinoma

Papillary thyroid carcinoma (PTC) is the most common type of thyroid malignancy and BRAF
V600E mutation is the most common genetic alteration identified in PTC, ranging from 25 to
80%, with the average rate about 45%. Various studies demonstrated a relationship between
BRAF V600E mutation and aggressive characteristics of the cancer, including the worse
patient prognosis. But,there are no studies from Turkey regarding this topic. So the
investigators will examine BRAF V600E mutation in our patients with PTC and try to assess
the role of this mutation in prognosis and further management of the patients.