Inclusion Criteria:

- Female

- At least one prescription for bazedoxifene, raloxifene, or any bisphosphonate during
the study inclusion period (index prescription);

- A recoded diagnosis code of osteoporosis on or within 60 days prior to the index
prescription date;

- Age >=45 at the date of the index prescription; and

- At least 6-months of follow-up data in the electronic medical record system prior to
the date of the index prescription

Exclusion Criteria:

- There is no exclusion criteria. All women in the database who meet the inclusion
criteria will be studied.