Women With Polycystic Ovary Syndrome Have Increased Plasma Chitotriosidase Activity: A Pathophysiological Link Between Inflammation and Impaired Insulin Sensitivity?
N/A
18 Years
35 Years
18 Years
35 Years
Not Enrolling
Female
Polycystic Ovary Syndrome
Female
Polycystic Ovary Syndrome
Trial Information
Women With Polycystic Ovary Syndrome Have Increased Plasma Chitotriosidase Activity: A Pathophysiological Link Between Inflammation and Impaired Insulin Sensitivity?
ChT activity is increased in patients with PCOS in concordance with insulin resistance.
These findings may reflect the pronounced risk for metabolic syndrome and atherosclerotic
diseases in this particular patient group.
Inclusion Criteria:
- Absence of significant abnormalities on physical examination except hirsutism
- no lipid lowering, hypoglycemic, antihypertensive or hormone replacement therapy
- normal thyroid function and prolactin level
- absence of history or evidence of metabolic, cardiovascular, respiratory or hepatic
disease
Exclusion Criteria:
- Pregnant
- ovarian tumors
- congenital adrenal hyperplasia or BMI greater than 30 kg/m2
Type of Study:
Observational
Study Design:
Observational Model: Case Control, Time Perspective: Cross-Sectional
Principal Investigator
Aydogan Aydogdu, MD
Investigator Role:
Principal Investigator
Investigator Affiliation:
No organizational affiliation
Authority:
Turkey: Ministry of Health
Study ID:
1491-81-11/1539-1563
NCT ID:
NCT01382576
Start Date:
January 2010
Completion Date:
December 2010
Related Keywords:
- Polycystic Ovary Syndrome
- polycystic ovary syndrome
- chitotriosidase activity
- Polycystic Ovary Syndrome
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