Trial Information

Circumferential Submucosal Incision Endoscopic Mucosal Resection Versus Conventional Endoscopic Resection for the Removal of Large Laterally Spreading Tumours and Sessile Polyps of the Colon

The investigators have recently developed a new, and the investigators believe safer and
more effective technique for endoscopic mucosal resection (EMR). Utilising the new method
the investigators make small cuts around the polyp to isolate it. Subsequently the
Gelofusine solution is injected beneath the polyp and provides greater elevation. This
allows us to improve the chance of removal of the entire polyp with one attempt in one
piece. It is preferable to remove the polyp in one piece as it minimises the chance of
leaving residual polyp tissue behind. Our team has recently completed an animal study
comparing our newly developed technique to conventional EMR. The investigators have found
significant improvements in our ability to completely remove the polyp in one attempt. There
have also been recent studies overseas that have shown this new technique to be quite
effective.