A Study to Assess and Quantify Surface Insulin-like Growth Factor I Receptor (IGF-IR) in Rhabdomyosarcoma (RMS) Tumor Tissue
- To determine and quantify the degree of surface insulin-like growth factor I receptor
(IGF-IR) expression in rhabdomyosarcoma (RMS) tumor tissue.
- To assess the feasibility and validity of a mass spectrometry assay for IGF-IR
expression on paraffin-embedded tumor tissue.
OUTLINE: Paraffin-embedded tumor tissue slides are analyzed for insulin-like growth factor I
receptor (IGF-1R) expression by mass spectrometry and correlated with the results obtained
by IHC assay.
Degree of surface IGF-IR expression in RMS tumor tissue
Suman Malempati, MD
Doernbecher Children's Hospital at Oregon Health and Science University
United States: Federal Government