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Contrast-enhanced Ultrasound for the Evaluation of Complex Renal Cysts

18 Years
Not Enrolling
Complex Renal Cyst

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Trial Information

Contrast-enhanced Ultrasound for the Evaluation of Complex Renal Cysts

By evaluating complex renal cysts using a contrast-enhanced ultrasound (CEUS), it can be
established as to whether or not the results are better, the same, or worse, when compared
to CT and/or MRI scans.

Inclusion Criteria:

- at least 18 years old and capable of giving informed consent

- all patients undergoing CT evaluation of complex renal cysts at our centre (either
initially or in follow-up)

- A complex renal cyst defined as Bosniak IIF, III or IV

Exclusion Criteria:

- pregnant patients

- patients with contrast allergies

- patients with non-cystic, solid renal masses

- patients with simple cysts (Bosniak class I and II)

Type of Study:


Study Design:

Allocation: Non-Randomized, Intervention Model: Single Group Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Diagnostic

Outcome Measure:

concordance between CEUS and CT

Outcome Description:

Complex renal cysts will be classified using the Bosniak classification system for both the CEUS and CT and compared. If surgical removal of a complex cyst is required (Bosniak IIF, III or IV), then the pathology will be evaluated with a single CEUS and a CT (The CEUS will be conducted 14 days within the CT).

Outcome Time Frame:

(Baseline, follow up at 3, 6, 9, & 12 months)

Safety Issue:


Principal Investigator

Anil Kapoor, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

McMaster Institute of Urology - St. Joseph's Healthcare Hamilton


Canada: Ethics Review Committee

Study ID:




Start Date:

December 2013

Completion Date:

April 2015

Related Keywords:

  • Complex Renal Cyst
  • complex renal cysts
  • Contrast enhanced ultrasound
  • Cysts
  • Kidney Diseases, Cystic