Vitamin D and Fish Oil for Autoimmune Disease, Inflammation and Knee Pain
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Factorial Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Prevention
Serum levels of Biomarkers of Systemic Inflammation
Blood samples at baseline and in follow-up will be collected and analyzed for changes in biomarkers of systemic inflammation: C-reactive protein, interleukin-6, and tumor necrosis factor-receptor 2. We will test whether either or both supplements are associated with a decrease in the biomarkers of systemic inflammation (blood biomarker levels among those receiving supplements vs. placebo).
Karen H Costenbader, MD, MPH
Brigham and Women's Hospital
United States: Institutional Review Board
|Brigham and Women's Hospital||Boston, Massachusetts 02115|