Safe D3 Right Hemicolectomy for Cancer Through 3D MDCT Angiography Reconstruction
The Norwegian gastrointestinal cancer group has recommended D3 resection as the standard
operative technique for colon cancer. D3 resection implies ligation of the blood vessels at
their origin. There is evidence that the recurrence free period and survival improves with
the number of lymph nodes harvested at surgery. However, the current practice in Norway,
while performing right hemicolectomy for cancer is to ligate the feeding vessels for the
right colon on the right hand side of the superior mesenteric vein (SMV). Significant
arterial stumps have been demonstrated in patients operated for right colon cancer with this
technique (right colic artery and ileocolic artery vascular stumps with an average length of
3.5 cm and 2.5 cm, respectively). This leaves reason to believe that a certain number of
central lymph nodes remain after the procedure.
The complex anatomical relationship between the right colic artery and ileocolic artery with
the superior mesenteric vein make D3 resection demanding, especially if the right colic
artery lies posterior to the SMV. These relationships are investigated in detail in
postmortem anatomical studies. These studies show that the right colic artery lies most
often anterior to the SMV, while the ileocolic artery lies most often posterior to the SMV.
Data has also been provided that a CT angiography can verify these relations as well as
postmortem anatomical studies in living patients, thus allowing the surgeon to be aware of
them prior to surgery. This could prove to be crucial in planning the procedure.
Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Number of additional lymph nodes removed through radical D3 resection
The short term outcome of this study will compare number of lymph nodes removed, operating time and complications between the two groups.
Norway: Regional Ethics Commitee
D3 MDCT angio