Inclusion Criteria:

- Age: 40 to 80 years

- Language spoken: Finnish or Swedish

- Performance status: Karnofsky score 70 or better or WHO performance status 2 or
better

- Diagnosis: Histologically confirmed prostate or breast cancer

- Mental status: Patients must be able to understand the meaning of the study

- Informed consent: The patient must sign the appropriate Ethics Committee (EC)
approved informed consent documents in the presence of the designated staff

- strong suspicion of first bone metastatic disease (already diagnosed metastases in
other organs, elevated tumor markers, destruction of bone in plain x-ray or otherwise
specified reasons

- adjuvant chemo- or endocrine therapy is allowed

Exclusion Criteria:

- Ongoing treatment for metastatic disease

- Contraindications for MRI (cardiac pacemaker, intracranial clips etc.)

- Infections: Patient must not have an uncontrolled serious infection

- Claustrophobia