Inclusion Criteria:

- Patient aged over 16 at baseline.

- Viral Load (VL) > 5000 copies/ml at baseline (and measured in 6 months prior to
baseline).

- No changes in antiretroviral (ARV) regimens in the month period prior to baseline, or
on no ARVs in the month prior to baseline.

- > 3 months exposure (sequential or cumulative) to at least 3 of the following;

- Any nucleoside or nucleotide reverse transcriptase inhibitor (NRTI)

- Non-nucleoside reverse transcriptase inhibitor (NNNRTI)

- Protease Inhibitor (PI )

- Enfuvirtide

Exclusion Criteria:

None