Effects of Topical Dexpanthenol on Chemotherapy and Radiotherapy Induced Oral Mucositis
N/A
N/A
Both
Oral Mucositis (Ulcerative) Due to Radiation
Trial Information
Effects of Topical Dexpanthenol on Chemotherapy and Radiotherapy Induced Oral Mucositis
Patients will be given a bottle of 5% Dexpanthenol mouthwash and they are asked to rinse 10
ml of it three times a day. At the onset of mucositis and then for 4 subsequent weeks they
will be examined to evaluate the condition of their oral mucosa.By the advent of mucositis
stage 4 ,at any time during the 4 weeks of study,the patient would be out.if any patient
shows allergic reaction to dexpanthenol,he/she would be out of study too.
Inclusion Criteria:
1. without any systemic disease
2. estimated survival of at least 6 months
3. without any mental disorders
4. grade 1 to 3 WHO mucositis
Exclusion Criteria:
1. development of grade 4 WHO mucositis
2. Brachytherapy
3. allergy to the drug
4. dissatisfaction of the patient
Type of Study:
Interventional
Study Design:
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
Outcome Measure:
reduction of intensity of mucositis
Outcome Description:
measuring of the intensity of mucositis by visual examination and asking the patient about pain and discomfort
Outcome Time Frame:
first week (week one)
Safety Issue:
No
Principal Investigator
Fahimeh Anbari, resident
Investigator Role:
Principal Investigator
Investigator Affiliation:
dental faculty of shaheed Beheshti medical university
Authority:
Iran: Ministry of Health
Study ID:
BMU1360
NCT ID:
NCT01318889
Start Date:
September 2010
Completion Date:
September 2011
Related Keywords:
- Oral Mucositis (Ulcerative) Due to Radiation
- Dexpanthenol
- Radiotherapy
- chemotherapy
- Mucositis
- Stomatitis
- Ulcer
- Mucositis
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