Type of Study:

Interventional

Study Design:

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Investigator, Outcomes Assessor), Primary Purpose: Prevention

Outcome Measure:

Limb remote ischemic preconditioning has effective protection of lung injury in patients undergoing pulmonary lobectomy

Outcome Description:

Compared with the control group, patients in the LRIP group had significantly higher Cs and Cd , along with lower PA-aDO2 and RI at various phase (P<0.05). Serum concentration of IL-6,IL-8, TNF-ɑ and MDA in LRIP group were decreased significantly at postoperative time points compared with those in control group (P<0.05), but SOD was increased significantly at the same time (P<0.05).

Outcome Time Frame:

Jan,2012

Safety Issue:

Yes

Principal Investigator

Xuan Ke Liu, Ph.d

Investigator Role:

Principal Investigator

Investigator Affiliation:

Department of Anesthesiology, The First Affiliated Hospital, Sun Yat-sen University

Authority:

China: Ethics Committee

Study ID:

RIP1126

NCT ID:

NCT01307085

Start Date:

February 2011

Completion Date:

September 2012

Related Keywords:

• Lung Neoplasms
• remote ischemic preconditioning
• lung injury
• pulmonary lobectomy
• Neoplasms
• Lung Neoplasms
• Lung Injury