Inclusion Criteria:

- Must be male or female and at least 18 years of age

- Female patients must be of: non-childbearing potential or if of childbearing
potential then have a negative serum and urine pregnancy test and using effective
contraception

- Ability to provide informed consent

Exclusion Criteria:

- Have received treatment with immunomodulators, or interferon/interferon inducers or
systematic medications that suppress the immune system in the last 4 weeks

- Exposed to prescribed systemic (take as tablet, injection etc) or topical (gel,
cream, lotion) medication within the last 7 days

- Have any signs of skin irritation or damaged skin at or around the dominant index
finger

- Have worked in an occupation with a high risk of being in contact with irritative
material (eg. chemicals, painting) on their hands, especially fingers

- Those who are currently participating in any other clinical trial

- Those known or suspected of not being able to comply with the requirements of the
protocol

- Females who are pregnant or are breastfeeding