Inclusion Criteria
Inclusion criteria:
- RA fulfilling the criteria of the american college of rheumatology (ACR) (revised
1987)
- 18 years and older
- Cervical pain
- Recent MRI with detectable atlanto-axial pannus
Exclusion criteria:
- Use of TNF-inhibitors 3 months prior to inclusion
- Previous treatment with any biologics other than TNF-Blockers
- History of inflammatory joint disease other than RA
- History of active tuberculosis, histoplasmosis or listeriosis
- History of lymphoma or other malignancies within 5 years
- Contraindication for the use of TNF inhibitors
- Comorbidities: severe myocardial dysfunction, recent stroke (within 3 months),
uncontrolled diabetes and other disease which in the opinion of the investigator,
would put the subject at risk by participation in the trial
- History of demyelinating disorders
- Persistent or recurrent infections
- Pregnancy or breast feeding