Role of Natural Fluorescence of Human Blood Plasma in Patients With Colorectal Cancer.
Eligibility criteria: Gastrointestinal disease or clinical symptoms related to colorectal
cancer risk submitted to endoscopy. Exclusion criteria consisted of age younger than 18
years, history of psychiatric illness, and preoperative radiotherapy.
Outcome: investigated the possible role of the native fluorescence of blood plasma in the
management of colorectal cancer (CRC) and its feasibility as a new tumor marker. Sample of
blood was collected from asymptomatic blood donors and from CRC patients. The native
fluorescence of blood plasma was measured using a conventional spectrofluorimeter.
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Screening
Colorectal cancer detection by means of optical fluoroscopy
investigated the possible role of the native fluorescence of blood plasma in the management of colorectal cancer (CRC) and its feasibility as a new tumor marker.
alberto vannelli, md
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Italy: Ethics Committee