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APPLICATION OF CONTINUOUS POSITIVE AIRWAY PRESSURE IN POSTOPERATIVE OF LUNG RESECTION


N/A
40 Years
75 Years
Not Enrolling
Both
Lung Cancer, Pulmonary Complications

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Trial Information

APPLICATION OF CONTINUOUS POSITIVE AIRWAY PRESSURE IN POSTOPERATIVE OF LUNG RESECTION


In pulmonary resection surgery complications that lead to significant functional losses of
the lung parenchyma and alterations in the ventilatory function may trigger retention of
secretions, atelectasis, pneumonia and respiratory failure, which prolong the duration of
mechanical ventilation and hospitalisation and contribute to the increase in risk of
mortality.

In this study the oxygenation index (OI), Borg Scale, pain scale and the presence and
duration of thoracic drainage was determined in the immediate postoperative (POi) period and
in the first and second postoperative (PO1, PO2) days in 40 patients who underwent elective
lung resection.

Similar to Chest Physiotherapy, the preventive application of CPAP in the postoperative
period after lung resection in our study also appeared to be a safe technique, which allowed
improved oxygenation without increasing air leaks through the thoracic drains.


Inclusion Criteria:



- medical diagnosis of lung cancer and an indication for lung resection (lobectomy,
bilobectomy and pneumonectomy) with posterolateral thoracotomy;

- aged between 40 and 75 years.

Exclusion Criteria:

- Patients who refused to participate in the survey;

- lung resection with incisions other than posterolateral;

- patients who had contraindications to the use of noninvasive ventilation.

Type of Study:

Interventional

Study Design:

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Factorial Assignment, Masking: Open Label, Primary Purpose: Treatment

Outcome Measure:

Bubbling drains

Outcome Description:

From the immediate postoperative day until hospital discharge, the presence of chest tubes and the occurrence of air leaks in them as evidenced by the bubbling of the water seal were recorded. The maintenance and removal of drains or their use with wall suction were determined by applying the medical protocol of the institution through the analysis of X-rays and the amount of drained fluid.

Outcome Time Frame:

From immediate postoperative until fifth, along the study, in a total of one year

Safety Issue:

Yes

Principal Investigator

Lígia S. Roceto

Investigator Role:

Principal Investigator

Investigator Affiliation:

University of Campinas, Brazil

Authority:

Brazil: Ethics Committee

Study ID:

ROCETO130682

NCT ID:

NCT01285648

Start Date:

November 2007

Completion Date:

February 2010

Related Keywords:

  • Lung Cancer
  • Pulmonary Complications
  • chest tubes,
  • Continuous Positive Airway Pressure,
  • lung resection, thoracic surgery,
  • noninvasive ventilation,
  • postoperative
  • Lung Neoplasms

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