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The Correlation Between Lung Cancer Susceptibility, Drug Response and Genetic Polymorphism


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20 Years
N/A
Open (Enrolling)
Both
Lung Cancer

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Trial Information

The Correlation Between Lung Cancer Susceptibility, Drug Response and Genetic Polymorphism


The current study is a matched case-control study. The experimental group is the patients
diagnosed as lung cancer at Taipei Medical University- Wanfang Hospital from January 2010 to
December 2013, and one healthy patient will be matched to each case as the control group.
The purpose of the current study is to investigate the association between genetic
polymorphisms and lung cancer in the Taiwanese population and to analyze the correlation.


Inclusion Criteria:



- This study has two groups, the case group and the control group. The match criteria
is patients with the same gender and the age is ± 5 years.

1. Case group - Patients with the pathology diagnosed as the primary lung cancer
patients.

2. Control group - Patients without any cancer or disease history of cancers.

Exclusion Criteria:

- Case group - Patients with the pathology diagnosed as the non-primary lung cancer
patients or the patients with lung cancer induced by other cancer metastasis.

- Control group -

1. With other cancers.

2. With COPD induced by smoking or the genetic factors.

3. With familial adenomatous polyposis

4. With HIV infection, hepatitis B or hepatitis C

Type of Study:

Observational

Study Design:

Observational Model: Case Control, Time Perspective: Prospective

Principal Investigator

Hsin-Gjin Eugene Liu

Investigator Role:

Principal Investigator

Investigator Affiliation:

Taipei Medical University WanFang Hospital

Authority:

Taiwan: Department of Health

Study ID:

99054

NCT ID:

NCT01280448

Start Date:

September 2010

Completion Date:

September 2013

Related Keywords:

  • Lung Cancer
  • Lung Cancer
  • Tobacco Smoking
  • gene polymorphism
  • Disease Susceptibility
  • Lung Neoplasms

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