Trial Information
The Correlation Between Lung Cancer Susceptibility, Drug Response and Genetic Polymorphism
The current study is a matched case-control study. The experimental group is the patients
diagnosed as lung cancer at Taipei Medical University- Wanfang Hospital from January 2010 to
December 2013, and one healthy patient will be matched to each case as the control group.
The purpose of the current study is to investigate the association between genetic
polymorphisms and lung cancer in the Taiwanese population and to analyze the correlation.
Inclusion Criteria:
- This study has two groups, the case group and the control group. The match criteria
is patients with the same gender and the age is ± 5 years.
1. Case group - Patients with the pathology diagnosed as the primary lung cancer
patients.
2. Control group - Patients without any cancer or disease history of cancers.
Exclusion Criteria:
- Case group - Patients with the pathology diagnosed as the non-primary lung cancer
patients or the patients with lung cancer induced by other cancer metastasis.
- Control group -
1. With other cancers.
2. With COPD induced by smoking or the genetic factors.
3. With familial adenomatous polyposis
4. With HIV infection, hepatitis B or hepatitis C
Type of Study:
Observational
Study Design:
Observational Model: Case Control, Time Perspective: Prospective
Principal Investigator
Hsin-Gjin Eugene Liu
Investigator Role:
Principal Investigator
Investigator Affiliation:
Taipei Medical University WanFang Hospital
Authority:
Taiwan: Department of Health
Study ID:
99054
NCT ID:
NCT01280448
Start Date:
September 2010
Completion Date:
September 2013
Related Keywords:
- Lung Cancer
- Lung Cancer
- Tobacco Smoking
- gene polymorphism
- Disease Susceptibility
- Lung Neoplasms