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PREOPERATIVE CHEMOTHERAPY DOES NOT ADVERSELY AFFECT SHORT-TERM OUTCOME AFTER PANCREATIC RESECTION.


N/A
18 Years
80 Years
Not Enrolling
Both
Locally Advanced Pancreatic Adenocarcinoma

Thank you

Trial Information

PREOPERATIVE CHEMOTHERAPY DOES NOT ADVERSELY AFFECT SHORT-TERM OUTCOME AFTER PANCREATIC RESECTION.


Between 2003 and 2011, patients with locally advanced (stage III) pancreatic cancer who were
treated with preoperative chemotherapy (PCHT) underwent surgical resection. Each patient was
matched with the closest two patients with pancreatic cancer ( control group ) selected from
our prospective electronic database who met the following match criteria: age (+/- 3
years), gender, ASA score, type of resection, pancreatic duct diameter (+/- 1 mm), and
tumour size (+/- 5 mm).


Inclusion Criteria:



- Diagnosis of pancreatic cancer

- Preoperative chemotherapy

- Pancreatic resection

Exclusion Criteria:

- Metastatic disease

- ASA score 4

Type of Study:

Interventional

Study Design:

Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Outcome Measure:

Postoperative morbidity rate

Outcome Time Frame:

Postoperative. From 0 to 30 days after discharge

Safety Issue:

No

Principal Investigator

Marco Braga, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Università Vita-Salute San Raffaele

Authority:

Italy: Ministry of Health

Study ID:

NEOADJUVANT_MATCH

NCT ID:

NCT01278368

Start Date:

January 2003

Completion Date:

December 2011

Related Keywords:

  • Locally Advanced Pancreatic Adenocarcinoma
  • pancreatic cancer, neoadjuvant chemotherapy
  • Adenocarcinoma
  • Adenocarcinoma, Mucinous

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