Inclusion Criteria:

- Children from 6 months to 18 year-old.

- PWS of the face

- No prior treatement with PDL

- Membership or beneficiary of a national insurance scheme.

- Consent signed by the parents and by the patient if he is old enough to understand

Exclusion Criteria:

- Child with whom the angioma plan was already handled by laser or pulsed lamp

- Histories of asthma or obstructive bronchitis

- severe allergic Rhinitis and hyper bronchial ability to react

- Bradycardie sinusale, block auriculo-ventriculaires of the second or third degree

- unchecked Cardiac insufficiency

- cardiogenic Shock

- untreated Phéochromocytome

- Sentimentality in the timolol or in one of these excipients, and\or in the other
bétabloquants

- Taken by floctafénine or by sultopride

- Taken of bétabloquants by oral route, of inhibitors calcic or of amiodarone

- severe peripheral circulatory Disorders(Confusions of Raynaud)

- arterial Low blood pressure

- Pregnancy and feeding

- Absence of effective contraception at the girls old enough to procreate

- Contraindication in the use of cream with lidocaïne and with prilocaïne