High Dose Rate (HDR)Prostate Brachytherapy With Vitesse tm
Fifteen men with intermediate risk prostate cancer, suitable for the combination of external
beam radiotherapy and High Dose Rate brachytherapy will be entered in this study. High Dose
Rate brachytherapy will be performed using TransRectal UltraSound guidance and then planned
using both cone-beam Computed Tomography and TransRectal UltraSound. Planning by Computed
Tomography is to check the reliability and reproducibility of UltraSound imaging to
correctly identify the needle positions. Correct needle localization is essential because
this is the basis for determining source dwell positions, dose calculation and dose
optimization.
Interventional
Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Quality assessment of TransRectal Ultra-sound based plan for High Dose Rate prostate brachytherapy compared to Computed Tomography-derived plan
The dosimetric quantifiers (V100: percentage of prostate volume covered by 100% prescription isodose, V150: percentage of prostate volume enclosed by 150% of prescription dose, urethral dose and rectal dose)will be used to determine differences between Ultra-sound based plan and the standard Computed Tomography-image based plan
6 weeks
No
Matthew Schmid, MSc
Study Director
British Columbia Cancer Agency Dept of Radiation Physics
Canada: Health Canada
H10-01987
NCT01248741
December 2010
May 2012
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