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Multicentric Retrospective Case Control Study of the Impact of Hypersplenism and Splenectomy on Hepatocarcinogenesis in Patients With Posthepatitic Cirrhosis


N/A
20 Years
90 Years
Open (Enrolling)
Both
Liver Cirrhosis, Carcinoma, Hepatocellular, Splenomegaly, Laparotomy

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Trial Information

Multicentric Retrospective Case Control Study of the Impact of Hypersplenism and Splenectomy on Hepatocarcinogenesis in Patients With Posthepatitic Cirrhosis


A case-control study was carried out. The factors studied include age, gender, ascites,
hepatic encephalopathy, ALT, AST, TBIL, ALP, GGT, Child-Pugh classification of liver
function, and history of splenectomy with portal-azygous disconnection during the treatment
of portal hypertension. According to the Child-Pugh classification, these cases were graded
as A, B, and C. And according to the ranges of the normal reference values of the data, they
were categorized into two groups including a normal group and an abnormal group.The data
mainly comes from FMMU and Xi'an jiaotong university from the year of 2002 to 2012.


Inclusion Criteria:



- after surgery

Exclusion Criteria:

- without surgery

Type of Study:

Observational

Study Design:

Observational Model: Case Control, Time Perspective: Retrospective

Principal Investigator

Chen yong, professor

Investigator Role:

Study Director

Investigator Affiliation:

Xia jielai

Authority:

China: Food and Drug Administration

Study ID:

chenyong

NCT ID:

NCT01201655

Start Date:

January 2010

Completion Date:

December 2012

Related Keywords:

  • Liver Cirrhosis
  • Carcinoma, Hepatocellular
  • Splenomegaly
  • Laparotomy
  • Posthepatitic cirrhosis;
  • Hepatocarcinogenesis;
  • Splenectomy;
  • Carcinoma
  • Hypersplenism
  • Liver Cirrhosis
  • Fibrosis
  • Splenomegaly
  • Carcinoma, Hepatocellular

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