A Prospective Study to Evaluate the Feasibility of Partial Breast Irradiation Utilizing Permanent Breast Seed Implant in British Columbia
Endpoint Classification: Safety Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Technical parameters of the implant
Implant technical parameters will include: SC (Surgical Cavity/Seroma) volume (average & range) PTV (average & range) Number of seeds per implant (average & range) Average total seed activity per implant From DVH, average and range of: V90 V100 V150 V200 DHI Number of seeds at a distance 5 mm or less from the skin surface Absolute (cc) and proportional (%) volume of ipsilateral breast receiving 90%, 50% and 10 % of the prescribed dose
Measured once for each subject at a post-implant CT on the same day as the implant procedure. Will be assessed collectively once treatment is completed for all 5 subjects.
Hosam A Kader, MD
BCCA, Department of Radiation Oncology
Canada: Health Canada