Inclusion Criteria:

- 1) Histological confirmed prostatic carcinoma patient

- 2) Hormone non-respondence ex1) Although treatment PSA ≥ 5ng/ml ex2) PSA level were
measured two times ex3) Prior one year radiology were processed

- 3) Just 18 years over

- 4) Has a score ≤1 on the ECOG Performance Scale

- 5) Expected survival life time ≥ 6month

- 6) Adequate bone marrow function hemoglobin ≥ 10.0g/dL , leukocyte count ≥ 4,000/mm3
thrombocyte ≥ 100,000/mm3

- 7) Adequate blood coagulation function PT(INR) < 1.5, aPTT< 1.5 x control

- 8) Adequate kidney function Normal blood upper level Creatinine ≤ 1.5 times

- 9) Adequate liver function Normal blood upper level AST/ALT ≤ 1.5 times

- 10) Autoimmune antibody system don't have disorder ex) anti-nuclear antibody,
anti-thyroglobulin antibody negativity

- 11) Person who didn't treat prior 6 weeks operation, radiotherapy
treatment,immunotherapy or chemotherapy

- 12) Patient who voluntarily participated clinical trial and confirmed a written
consent

Exclusion Criteria:

- 1) Having other malignancy or previous history of malignancy

- 2) Brain metastases patient

- 3) Having autoimmune disease or its history

- 4) Pyrexia, rigor, leukocytosis infectious disease

- 5) HBsAg, anti-HCV, HIV positive patient

- 6) Myocardial infarction, cardiac insufficiency, other severe heart disease and
non-controlled hypertension

- 7) Severe and active medical disease

- 8) Mental history disease or epilepsy

- 9) Patients participated other clinical trial within 4 weeks

- 10) Patients impossible to participate this trial by investigator's decision

- 11) Patients who received immunosuppressant such as steroid, cyclosporin A,
azathioprine within 6 weeks