Trial Information

A Feasibility Study to Compare the Benefits of Endoscopic Tumor Clip Placement and 3T-MRI Simulation for Accurate Target Volume Definition for Rectal Cancer Patients Undergoing Pre-operative Chemoradiation

1. The use of endoscopically placed mucosal metal clips to define the superior and
inferior extent of the rectal tumor will improve the accuracy of tumor localization in
patients undergoing non-contrast CT simulation.

2. A 3T-MRI will provide a better localization of the rectal tumor and pelvic nodes
compared to non-contrast CT simulation for radiotherapy treatment planning.

3. By comparing these two novel methods to the standard procedure, we would be able to
define any difference between the three methods and obtain an estimate of the accuracy
and reliability of each method for the localization of the rectal tumor.