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Determination of a Possible Association of Fundic Gland Polyps With the Use of Proton Pump Inhibitor Drugs


N/A
18 Years
85 Years
Not Enrolling
Both
Fundic Gland Polyps

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Trial Information

Determination of a Possible Association of Fundic Gland Polyps With the Use of Proton Pump Inhibitor Drugs


Inclusion Criteria:



- Age 18 and above.

- Able and willing to sign informed consent.

- The patient had a gastric fundic gland polyp detected on EGD that was removed and
sent to pathology or patient had no fundic gland polyps on EGD but are on PPIs and
will serve as controls.

Exclusion Criteria:

- Unwilling or unable to sign informed consent for the study.

Type of Study:

Observational

Study Design:

Observational Model: Case Control, Time Perspective: Prospective

Outcome Measure:

Number of patients with fundic gland polyps and PPI use that have a higher gastric pH

Outcome Description:

We aim to examine clinical parameters, including history of PPI use and fasting gastrin levels, as well as histologic characteristics (particularly the presence of ECL-cell hyperplasia) of patients found to have fundic gland polyps during endoscopy. We believe there is a correlation between fundic gland polyps of the stomach and use of proton pump inhibiter medications.

Outcome Time Frame:

Up to 1 year

Safety Issue:

No

Principal Investigator

Harold Frucht, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Columbia University

Authority:

United States: Institutional Review Board

Study ID:

AAAC2805

NCT ID:

NCT01130363

Start Date:

October 2006

Completion Date:

April 2012

Related Keywords:

  • Fundic Gland Polyps
  • Proton Pump Inhibitor
  • Gastric carcinoid tumors
  • Gastric cancer
  • Fundic Gland Polyps
  • Polyps

Name

Location
Columbia University Medical Center New York, New York  10032